Top 10 Rarest Diseases You've Never Heard Of

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There are some mystery diseases you may never have heard of. From Foreign Accent Syndrome, to the Tree Man Illness, to Hutchinson-Gilford Progeria Syndrome – which inspired “The Curious Case of Benjamin Button” – these are some of the strangest known medical conditions. WatchMojo counts down ten fascinating rare illnesses.

Want to scare yourself into hypochondria even more? Check out our videos on the Top 10 Diseases That Kill You Quickly:, Top 10 Most Dangerous Surgeries: and Top 10 Worst Epidemics in History:

00:44 #10: Foreign Accent Syndrome
01:48 #9: Microcephaly
02:32 #8: Epidermodysplasia Verruciformis
03:18 #7: Fibrodysplasia Ossificans Progressiva (FOP)
04:00 #6: Hutchinson-Gilford Progeria Syndrome
04:50 #5: Harlequin-Type Ichthyosis
05:39 #4: Congenital Analgesia
06:24 #3, #2 & #1???

Special thanks to our users Ayoub Mahmoud, Dubstep Choo Chen Ling, MikeMJPMUNCH, EmJay and RedHood for suggesting this idea! Check out the voting page at

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